Drug Designer

Schrödinger’s mission is to revolutionize drug discovery through the use of breakthrough computational methods.  We are currently looking for outstanding individuals to join our drug discovery group and contribute to our rapidly expanding portfolio of drug discovery collaborations.

Our drug discovery group of over 60 scientists includes designers, modelers, computational chemists, medicinal chemists, crystallographers, biochemists, and biologists with experience working on all common target classes and therapeutic areas. The group is supported by more than 100 software developers and engineers as well as a large scale compute infrastructure. Four of the programs we’ve worked on in the past 7 years have progressed into the clinic; two are still progressing through trials and two have been approved by the FDA.  

If you are a medicinal or organic chemist and have an interest in applying cutting-edge computational approaches to structure-enabled projects, we are eager to hear from you.

Responsibilities
  • Play a key role in our drug discovery projects
  • Design molecules and virtual libraries to meet project goals
  • Work closely with collaborators and other members of the drug discovery group to drive programs and our technology forward

Essential Qualifications and Experience
  • Ability to design compounds in a 3D structure-based environment
  • Understanding of protein-ligand interactions
  • Understanding of small molecule conformations, and ionization and tautomeric states
  • Ph.D. in organic or medicinal chemistry
  • Some modeling experience
  • Exceptional communication skills

Desirable Skills
  • Practical understanding of the application of physical organic chemistry principles to drug discovery
  • Computational chemistry experience

We offer highly competitive compensation packages. Benefits include medical, dental, vision, 401(k), flexible spending account, 4+ weeks vacation, tuition reimbursement and a flexible work environment.

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, national origin, citizenship status, marital status, union status, sexual orientation, or gender identity. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.

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