Job Summary:
Arbor Biotechnologies is seeking an experienced individual to lead structural biology efforts for our newly discovered protein systems. Structural biology is a key component for translating our discovery into therapeutic application. As Principal Scientist, you will be responsible for initiating and developing structure biology pipelines through both internal initiatives and CROs. You will also be expected to use structural knowledge to provide mechanistic insights of protein systems, and work with protein engineers to guide structure-based designs and evaluate protein engineering and product development projects. You will be working with highly interdisciplinary teams to meet deadlines, achieve team objectives, and demonstrate key results. Previous industry experiences and management of a team and CROs are highly preferred.
Responsibilities:
- Establish a structural biology program and lead a team to guide and support protein engineering and application development
- Provide leadership and expertise in structural characterization and structure-based design
- Perform protein expression and purification, crystallizing, X-ray structure determination and/or Cryo-EM structure determination through both internal initiatives and CROs
- Interact and manage collaborations with both internal teams and CROs
Requirements:
- A Ph.D in structural biology and related fields with additional 2-5 years of experiences
- Demonstrated ability to solve multiple protein structures and tackle difficult problems in protein crystallography, structural biology and biophysics
- Extensive knowledge of protein structure and function, with familiarity with structural modeling and design
- Excellent project management and organizational skills
- Integrity, creativity, drive, and collaboration
Preferred qualifications:
- Ability to start as soon as possible
- Strong knowledge or experience with both X-ray crystallography and Cryo-EM techniques
- Strong knowledge or experience with structural modeling and design, and molecular dynamics
- Industrial experience with managing external structural biology collaborations (CROs)
- 2+ years of relevant industry experience and minimum commitment of 2 years
About Arbor:
Arbor Biotechnologies is a venture-backed startup based in Cambridge, MA, composed of a small team of scientists and engineers pushing the boundaries of discovery at the intersection of computer science and biotechnology. Using our diverse backgrounds ranging from machine learning to genome engineering to protein biochemistry, we are building a platform to uncover and characterize nature’s inventions on an unprecedented scale to generate impactful applications in human health and sustainability.
We seek highly motivated individuals with the dedication, integrity, and creative spirit needed to thrive in an innovative company. Working at Arbor offers a unique opportunity that combines the fast pace and growth opportunities of a startup with the intellectual rigor and creativity of academia. Our salaries are competitive, our benefits are generous, and our team is exceptional.
Arbor Biotechnologies is proud to be an inclusive workplace and an Equal Opportunity Employer.